St. John's Wort for Depression

Wirksamkeit

St. John's wort rates as a likely effective treatment for depression. There are more than 10 studies which confirm its effectiveness.
 

Dosierung

People in studies most commonly take 300 mg three times daily for up to 6 weeks.
 

Sicherheit

St. John's wort rates as wahrscheinlich sicher when used orally. There are more than 10 studies which confirm its safety.
 

Nebenwirkungen

St. John's wort is usually well tolerated when used in typical doses.
 
Side effects can include:
  • Schlaflosigkeit
  • lebhafte Träume
  • Unruhe
  • Angst
  • Agitation
  • Reizbarkeit
  • gastrointestinal (GI) discomfort
  • Durchfall
  • Müdigkeit
  • trockener Mund
  • Schwindel
  • Kopfschmerzen
 
St. John's wort can also cause skin rash, paresthesia, and hypoglycemia.
 
Decrease insomnia by decreasing the dose or taking St. John's wort in the morning.
 
People treated with St. John's wort had side effects like the placebo. Side effects are less than conventional antidepressants.
 

Wechselwirkungen

Alprazolam (Xanax). Do not take this combination.
Verhütungsmittel.  Do not take this combination.
Cyclosporine (Neoral, Sandimmune).  Do not take this combination.
Digoxin (Lanoxin).  Do not take this combination.
Docetaxel (Taxotere).  Do not take this combination.
Imatinib (Gleevec).  Do not take this combination.
Irinotecan (Camptosar).  Do not take this combination.
Ketamine (Ketalar).  Do not take this combination.
Mephenytoin (Mesantoin).  Do not take this combination.
Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs).  Do not take this combination.
Omeprazole (Prilosec).  Do not take this combination.
Oxycodone (Oxycontin).  Do not take this combination.
P-glycoprotein Substrates.  Do not take this combination.
Phenobarbital (Luminal).  Do not take this combination.
Phenprocoumon (Marcoumar, Others).  Do not take this combination.
Phenytoin (Dilantin).  Do not take this combination.
Protease Inhibitors (PIs).  Do not take this combination.
Tacrolimus (Prograf).  Do not take this combination.
Warfarin (Coumadin).  Do not take this combination.

Aminolevulinic acid.  Seien Sie vorsichtig mit dieser Kombination.
Barbiturate. Seien Sie vorsichtig mit dieser Kombination.
Bupropion (Wellbutrin).  Seien Sie vorsichtig mit dieser Kombination.
Clopidogrel (Plavix).  Seien Sie vorsichtig mit dieser Kombination.
Clozapine (Clozaril).  Seien Sie vorsichtig mit dieser Kombination.